Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya

CORRELATION BETWEEN DEPRESSION LEVELS AND HYPERTENSION INCIDENCE AT THE RESILIENT ELDERLY SCHOOL (SELANTANG) IN PASURUAN CITY, EAST JAVA

Wed, 30 Apr 2025 00:00:00 +0000

Hypertension is a global health issue, particularly among the elderly, and can be influenced by psychological factors such as depression. This study investigated the relationship between depression and hypertension among the elderly in the SELANTANG community, Pasuruan City. Utilizing a cross-sectional design, the research involved 175 elderly participants from a total population of 240. Data were collected in August 2023 using the Geriatric Depression Scale (GDS) and blood pressure measurements. Results showed that most participants had isolated systolic hypertension, with an average systolic pressure of 142.58 mmHg and diastolic pressure of 83.00 mmHg. Despite a normal average depression score of 2, Spearman’s rank analysis indicated no significant correlation between depression levels and hypertension (p = 0.885 and p = 0.901). These findings suggest that hypertension management in the elderly should prioritize factors such as diet, lifestyle, and physical activity.

SIDE EFFECTS OF SECOND-LINE ANTITUBERCULOSIS DRUGS IN MULTI-DRUG RESISTANCE (MDR) TUBERCULOSIS PATIENTS

Wed, 30 Apr 2025 00:00:00 +0000

Multidrug-resistant tuberculosis (MDR TB) is caused by Mycobacterium tuberculosis strains resistant to isoniazid and rifampicin—the most potent anti-TB drugs. Prolonged treatment duration and complex drug regimens often lead to poor adherence, contributing to high MDR TB incidence and low treatment success rates, particularly in Indonesia. This study analyzed drug utilization patterns in 52 MDR TB patients at Dr. Mohammad Hoesin Hospital Palembang, using total sampling based on medical records from October 2018 to December 2019. Data were analyzed descriptively with SPSS v25. The most common side effects reported were weakness, nausea, and vomiting (84.6%), followed by arthralgia, hyperuricemia, and hearing loss (42.3%). Severe side effects were more prevalent in the short-term regimen group (40.4%) compared to the long-term group (7.7%). Weakness, nausea, and vomiting were the most frequently observed side effects in MDR TB patients.

PROFILE OF INTESTINAL PROTOZOAN PARASITES IN FARMING COMMUNITIES IN GISTING SUBDISTRICT, TANGGAMUS DISTRICT, LAMPUNG PROVINCE

Jhons Fatriyadi Suwandi, Fitria Saftarina, Juspeni Kartika — Wed, 30 Apr 2025 00:00:00 +0000

Intestinal parasitic infections remain a health problem in communities. Surveys of intestinal protozoan infections in Lampung Province are limited. The transmission of intestinal protozoan infections is generally through the oro-faecal route, which is related to environmental and behavioral factors. Farmers are one of the communities that are potentially infected. Gisting Sub District is one of the agricultural centers in Lampung Province. Farmers' contact with the environment will increase the risk of intestinal protozoan infection. This study aims to determine the Species of intestinal parasites found in farming communities. The design of this study is a descriptive observational survey. Feces collected were examined for parasitological examination at the Parasitology Laboratory, Faculty of Medicine, University of Indonesia. The results showed, the prevalence is 9.33%, consisting of Blastocystis sp. protozoa (6.67%), Entamoeba histolytica/dispar protozoa (1.33%), and a mixture of Blastocystis sp. and Endolimax nana (1.33%) among the research subjects.

CONTAMINATION OF SOIL-TRANSMITTED HELMINTH (STH) EGGS ON FLY VECTORS AT THE SUKAWINATAN FINAL DISPOSAL SITE (TPA) IN PALEMBANG CITY

Wed, 30 Apr 2025 00:00:00 +0000

In Indonesia, the prevalence of soil-transmitted helminths (STH) infection ranges from 2.5% to 62%, primarily affecting lower socioeconomic groups with poor sanitation. STH transmission can occur through fecal-oral routes, skin penetration of larvae, and mechanical vectors. This study examines STH egg contamination in flies at the Sukawinatan Landfill, Palembang, to understand their role in transmission and support vector control strategies. The research employs a descriptive observational study with a cross-sectional design. Observations were conducted microscopically with sample processed using the sedimentation technique. From 59 samples prepared from 598 flies, 17 samples (28.8%) were confirmed positive for STH eggs. The total number and type of STH eggs found were 24 Trichuris trichiura eggs. In conclusion, STH egg contamination was detected on flies at the Sukawinatan Landfill in Palembang City.

THE EFFECT OF INTERMITTENT FASTING 5:2 ON BODY FAT PERCENTAGE AND THICK UNDER-SKIN FAT FOLDS IN OVERWEIGHT AND OBESE INDIVIDUALS

Wed, 30 Apr 2025 00:00:00 +0000

Overweight and obesity is a condition in which there is an imbalance between the entry and exit of energy for a long time. Intermittent Fasting is one of the dietary interventions that can affect body composition such as body fat percentage and thick folds of fat under the skin. The purpose of this study was to determine the effect of Intermittent Fasting type 5:2 on body fat percentage and thick folds of fat under the skin in individuals with overweight and obesity. This study is an experimental study using pretest and posttest group design. The number of samples was 50 people with a consecutive sampling method. The statistical test used was the paired t-test. The results showed that intermittent fasting had a significant effect on body fat percentage (p<0.001), thick folds of fat under the skin of the biceps (p=0.009), and triceps (p<0.001), while the supra iliac and subscapular parts decreased but statistically insignificant (p=0.093) and (p=0.217).

THE ASSOCIATION BETWEEN BODY MASS INDEX (BMI) AND GASTROESOPHAGEAL REFLUX DISEASE (GERD) INCIDENCE AMONG VISITORS AT THE GASTROENTEROLOGY CLINIC OF RSUP DR. MOHAMMAD HOESIN PALEMBANG

Wed, 30 Apr 2025 00:00:00 +0000

This study aimed to determine the association between BMI and the incidence of GERD in visitors to the Gastroclinic of RSUP Dr. Mohammad Hoesin Palembang. A total of 153 samples met the eligibility requirements, this study used a random sampling technique and collected primary data through a questionnaire instrument. Data were analyzed using SPSS Statistic V27 in univariate, bivariate (chi-square test) and multivariate (logistic regression enter method) analysis. The majority of GERD patients were aged 36-65 years (46.7%), male sex (46.2%) and BMI in the obese category (65.9%). The results of this research showed no significant association among age and sex in the incidence of GERD, but there was a significant association between BMI on the incidence of GERD (p=0.003) thus being the most significant variable in this research (p=0.012). In conclusion, there is a significant association between BMI and the incidence of GERD while there is no significant association among age and sex in the incidence of GERD.

THE RELATIONSHIP BETWEEN LEUKOCYTE COUNT WITH TUBERCULOSIS (TB) LESION AREA IN CHEST X-RAY EXAMINATION

Nasywa Talitha Zahran, Yuyun Yueniwati, Alfred Julius Petrarizky — Wed, 30 Apr 2025 00:00:00 +0000

Leukocyte count is one of the hematological parameters known to help diagnose organ damage and serve as an indicator of the body's immune system. Leukocyte counts are associated with the extent of lesions in the lung fields of tuberculosis patients on Chest X-ray (CXR) examination. This study aims to evaluate whether the leukocyte count can be used as an alternative indicator for early detection and severity assessment of tuberculosis without relying on CXR results. Therefore, this study was conducted with the aim to determine the relationship between leukocyte count and TB lesion area from Chest X-ray (CXR) examination. This study is a quantitative research type of observational analysis with a cross sectional study design conducted on 60 research subjects derived from medical record data of TB patients at Saiful Anwar Hospital, Malang, from January 2022 to December 2023. The data obtained were analyzed using the Chi-Square method, which showed that there was no significant relationship between leukocyte count and the extent of TB lesions from the CXR examination (Chi-Square, p=0.706). The conclusion of this study is that leukocyte count is not associated with the description of the lesion area of TB patients.

DESCRIPTION OF KNOWLEDGE LEVEL, ATTITUDES, AND BEHAVIOR IN THE USE OF FACIAL WHITENING COSMETICS AMONG FEMALE STUDENTS OF THE FACULTY OF MEDICINE, HKBP NOMMENSEN UNIVERSITY MEDAN, 2024

Cory Anita Purba, Rudyn Raymond Panjaitan, Jenny Ria Sihombing — Wed, 30 Apr 2025 00:00:00 +0000

This is a descriptive study with a crossectional design. With the total sampling technique is obtained 71 female respondents who used whitening cosmetics. The results showed that the average age of the class of 2021 is 21.2 years, the average age of the class of 2024 is 20.2 years and the average age of the class of 2023 is 18.8 years. The description of the level of knowledge is sufficient (52.1%). The majority of the level of knowledge is found in the class of 2023 (59.1%). Description of the level of capable attitude (81.7%). The level of attitude that is able to be the majority in the class of 2022 (89.5%). The description of the level of behavior is quite capable (54.9%). The level of behavior is quite majority in the class of 2022 (79%).

THE RELATIONSHIP BETWEEN HISTORY OF HYPERTENSION AND ISCHEMIC ELECTROCARDIOGRAM FINDINGS IN CHRONIC HEART FAILURE PATIENTS

Zahra Maharani, Ni Made Elva Mayasari, Santhy Annisa, Yudi Fadilah — Wed, 30 Apr 2025 00:00:00 +0000

Heart failure is a condition in which the heart is unable to pump blood effectively throughout the body due to structural and functional impairments. It is a serious complication of hypertension, which can affect the heart's electrical activity and lead to abnormalities on electrocardiograms (ECG). This study aimed to determine the relationship between a history of hypertension and ECG abnormalities in chronic heart failure patients. This study used a cross-sectional study design, using primary data from ECG recordings, and ECG recording results interpreted by one expert. The study population included all chronic heart failure patients at the Cardiology Clinic of Muhammadiyah Palembang Hospital who met the inclusion and exclusion criteria. A total of 30 samples were analyzed. Among the patients, 25 (83,3%) had a history of hypertension. The results of the Fisher Exact Test statistical test between history of hypertension and abnormal ECG images obtained a value of p = 0,622 (p > 0.05). These findings indicate no association between a history of hypertension with ECG ischemic in chronic heart failure patients.

ANTIOXIDANT POTENTIAL AND HEALTH BENEFITS OF PURPLE SWEET POTATO LEAVES (IPOMOEA BATATAS L.)

Wed, 30 Apr 2025 00:00:00 +0000

Free radicals are molecules with one or more unpaired electrons, which makes them very labile and reactive. They are important in tissue damage and pathological processes in living organisms. Endogenous sources of free radicals are metabolic waste, such as combustion processes in the body, proteins, carbohydrates, and fats that we consume, and exogenous ones that come from air pollution, vehicle exhaust, and various chemicals and ultraviolet rays. 1, 2 An increase in free radicals can cause oxidative stress, resulting in oxidative damage from the cellular tissue to organ levels that will accelerate aging and cause various disease pathogenesis. 3 To reduce the impact of oxidative stress, adequate antioxidants are needed, which can be obtained from the body through enzymes or natural antioxidant intake. 4 One source of natural antioxidants comes from the leaves of purple sweet potato plants (Ipomea batatas L), which contain chemical compounds such as beta-carotene, bioflavonoids, catechins, and polyphenols that can ward off free radicals, improve oxidative stress conditions so that they are beneficial for maintaining health.

THE CORRELATION BETWEEN FAMILY SUPERVISION OF SCREEN TIME WITH THE INCIDENCE OF GADGET ADDICTION IN JUNIOR HIGH SCHOOL CHILDREN

Wed, 30 Apr 2025 00:00:00 +0000

Rapid technological developments have increased the use of gadgets among children and teenagers. Devices provide benefits in the form of easy access to information, but excessive use can have negative impacts, including adding gadgets. Children aged 12-15 years are the group most vulnerable to the negative impacts of gadgets. Families, especially parents, play an important role in supervising and guiding children in using devices. This research aims to determine the relationship between family supervision of screen time and the incidence of device addiction in junior high school children. This type of research is quantitative with a cross sectional design using primary data from the community of Kelurahan 5 Ulu Palembang with 91 samples that have met the inclusion and exclusion criteria. This research sample was taken by means of consecutive sampling. The results of the statistical test obtained a P-value of 0.000, so it can be concluded that there is a correlation between family supervision of screen time and the incidence of gadget addiction in junior high school children.

DISTRIBUTION AND INTENSITY OF MUSCULOSKELETAL PAIN AMONG RECREATIONAL DEADLIFT USERS IN PALEMBANG: A CROSS-SECTIONAL STUDY

Wardiansah Wardiansah, Indri Seta Septadina, Tri Suciati, Ricky Fajar Adipputra — Wed, 30 Apr 2025 00:00:00 +0000

Deadlift is a resistance training exercise commonly used to enhance muscle strength, but improper technique can increase the risk of musculoskeletal pain. This study aimed to analyze the distribution and intensity of musculoskeletal pain in recreational deadlift users using a cross-sectional design. A total of 42 respondents from two gym communities in Palembang were selected through purposive sampling. Data were collected via questionnaires and analyzed descriptively. The results showed that 48.9% of respondents had poor posture during deadlift, and the majority (66.7%) lifted heavy loads (≥70% of 1RM). Musculoskeletal pain was most frequently reported in the lower back (85.3%), followed by the glutes (8.8%) and the right shoulder (5.9%). Most respondents experienced mild pain (37.8%) or no pain at all (37.8%), while moderate pain was reported by 24.4% of respondents. No cases of severe pain were recorded. These findings indicate that although deadlift can cause musculoskeletal discomfort, the pain intensity is generally tolerable.

EFFECT OF DIABETIC RETINOPATHY PROGRESSION ON VISUAL ACUITY IN TYPE II DM PATIENTS

Ramzi Amin, Rajendra Ekki Maulana, Syarif Husin — Wed, 30 Apr 2025 00:00:00 +0000

This study aims to assess the effect of DR severity on visual acuity and to identify additional contributing factors. An observational analytic study with a cross-sectional design was conducted using medical records of Type II DM patients diagnosed with DR at Dr. Mohammad Hoesin General Hospital, Palembang, between January 2021 and October 2024. Statistical analysis was performed using Fisher’s exact test to evaluate significance, followed by logistic regression to determine the most influential factor. The results showed a significant association between DR severity and visual acuity (p=0.008), while other factors including macular edema (p=0.137), age (p=1.000), gender (p=1.000), intraocular pressure (p=1.000), HbA1c levels (p=1.000), and history of hypertension (p=1.000), were not significantly associated. In conclusion DR severity has a significant and dominant influence on the visual acuity of DR patients.

CCNE1 EXPRESSION AND CA-125 LEVELS IN HIGH GRADE SEROUS CARCINOMA OVARY AT MOHAMMAD HOESIN HOSPITAL PALEMBANG ; A SINGLE-INSTITUTION DESCRIPTIVE STUDY

Dianli Fitriani, Wresnindyatsih, Susilawati — Wed, 30 Apr 2025 00:00:00 +0000

High grade serous carcinoma (HGSC) of the ovary is the dominant subtype causing death from ovarian cancer. CCNE1 amplification occurs in 20% of ovarian HGSC and is associated with recurrence after platinum chemotherapy. Assessment of CCNE1 expression can be a screening for CCNE1 amplification. Measurement of CA-125 levels is routinely used for treatment monitoring and recurrence of HGSC patients. This study aims to assess CCNE1 expression, demographic characteristics and CA-125 levels of ovarian HGSC patients. Of the 31 HGSC patients, the study subjects were dominated by patients aged >50 years (61.3%), clinical stage FIGO III (64.5%), CCNE1 overexpression (71%), preoperative CA-125 levels ≥500 U/ml (77.4%) and postchemotherapy CA-125 levels <35 U/ml (58.1%).

DIGITAL CALIPER VS. INTRAORAL SCANNER: ACCURACY OF UPPER INTER-CANINE WIDTH MEASUREMENTS IN STUDY MODELS

Wed, 30 Apr 2025 00:00:00 +0000

The upper canine teeth exhibit significant sexual dimorphism, making them frequently used in gender identification in forensic odontology. The measurement of the inter-canine width can be performed using conventional methods, such as a digital caliper, or modern methods using an intraoral scanner. The intraoral scanner offers higher accuracy and easier data storage; however, no studies have compared the inter-canine width of the upper jaw using both methods. This study measured the inter-canine width of the upper jaw on 80 jaw models using both instruments, with each measurement performed three times per instrument. The measurement results were analyzed using SPSS, with Intraclass Correlation Coefficient (ICC) for agreement, Kolmogorov-Smirnov for normality, and Independent T-test for significance. The ICC results showed good agreement (0.892), and the Independent T-test revealed no significant difference (p = 0.598). It can be concluded that there is no significant difference between the measurement of the upper inter-canine width using the intraoral scanner and the digital caliper.