THE ASSOCIATION BETWEEN BODY MASS INDEX (BMI) AND GASTROESOPHAGEAL REFLUX DISEASE (GERD) INCIDENCE AMONG VISITORS AT THE GASTROENTEROLOGY CLINIC OF RSUP DR. MOHAMMAD HOESIN PALEMBANG
Main Article Content
This study aimed to determine the association between BMI and the incidence of GERD in visitors to the Gastroclinic of RSUP Dr. Mohammad Hoesin Palembang. A total of 153 samples met the eligibility requirements, this study used a random sampling technique and collected primary data through a questionnaire instrument. Data were analyzed using SPSS Statistic V27 in univariate, bivariate (chi-square test) and multivariate (logistic regression enter method) analysis. The majority of GERD patients were aged 36-65 years (46.7%), male sex (46.2%) and BMI in the obese category (65.9%). The results of this research showed no significant association among age and sex in the incidence of GERD, but there was a significant association between BMI on the incidence of GERD (p=0.003) thus being the most significant variable in this research (p=0.012). In conclusion, there is a significant association between BMI and the incidence of GERD while there is no significant association among age and sex in the incidence of GERD.
2. Ari Fahrial Syam, Chaidir Aulia, Kaka Renaldi, Marcellus Simadibrata Murdani Abdullah, Tjahjadi Robert Tedjasaputra. Revisi Konsensus Nasional Penatalaksanaan Penyakit Refluks Gastroesofageal (Gastroesophageal Reflux Disease/GERD) di Indonesia. II. Perkumpulan Gastroenterologi Indonesia (PGI);
3. Boulton KHA, Dettmar PW. A Narrative Review of The Prevalence of Gastroesophageal Reflux Disease (GERD). Ann Esophagus. Maret 2022;5:7–7.
4. Choe JW, Joo MK, Kim HJ, Lee BJ, Kim JH, Yeon JE, dkk. Foods Inducing Typical Gastroesophageal Reflux Disease Symptoms in Korea. J Neurogastroenterol Motil. 30 Juli 2017;23(3):363–9.
5. Dadang Makmun, Achmad Fauzi, Hasan Maulahela,, Rabbinu Rangga Pribadi. Konsensus Nasional Penatalaksanaan Penyakit Refluks Gastroesofageal (GERD) di Indonesia. Revisi 2022. 2022.
6. Dadang Makmun, Achmad Fauzi, SpPD, K-GEH, Hasan Maulahela, Rabbinu Rangga Pribadi. Konsensus Nasional Penatalaksanaan Penyakit Refluks Gasttroesofageal (GERD) di Indonesia. Revisi 2019. 2019.
7. Darnindro N, Manurung A, Mulyana E, Harahap A. Prevalence of Gastroesophageal Reflux Disease (GERD) in Dyspepsia Patients in Primary Referral Hospital. Indonesia J Gastroenterology Hepatology Dig Endosc. 21 Juli 2020;19(2):91–6.
8. Dirac MA, Safiri S, Tsoi D, Adedoyin RA, Afshin A, Akhlaghi N, dkk. The Global, Regional, and National Burden of Gastro-Oesophageal Reflux Disease in 195 Countries and Territories, 1990–2017: A Systematic Analysis For The Global Burden of Disease Study 2017. Lancet Gastroenterology Hepatology. Juni 2020;5(6):561–81.
9. Domingues G, Moraes-Filho JPPD. Gastroesophageal Reflux Disease: A Practical Approach. Arq Gastroenterology. Oktober 2021;58(4):525–33.
10. Hartoyo FZR, Tandarto K, Sidharta V, Tenggara R. The Association Between Coffee Consumption and Gastroesophageal Reflux Disease. 2022;23(1).
11. Karim S, Ali H, Zehra SN, Faryal A, Khalid T, Mujtaba G. Anthropometric Modification can be Useful for Gastro-Esophageal Reflux Disease Symptoms; Which Parameter Should be Targeted Most? In a Tertiary Care Hospital at Karachi. Med Forum 2019;30(8):59-63.
12. Kim O, Jang HJ, Kim S, Lee HY, Cho E, Lee JE, dkk. Gastroesophageal Reflux Disease and Its Related Factors Among Women of Reproductive Age: Korea Nurses’ Health Study. BMC Public Health. Desember 2018;18(1):1133.
13. Kim SY, Jung HK, Lim J, Kim TO, Choe AR, Tae CH, dkk. Gender Specific Differences in Prevalence and Risk Factors for Gastro-Esophageal Reflux Disease. J Korean Med Sci. 2019;34(21):e158.
14. Lu TL, Li SR, Zhang JM, Chen CW. Meta-Analysis on The Epidemiology of Gastroesophageal Reflux Disease in China. World J Gastroenterology. 7 Desember 2022;28(45):6410–20.
15. Pardede BTD, Laksmi LI. Relationship of Body Mass Index with Gastroesophageal Reflux Disease based on Gastroesophageal Reflux Disease Questionnaire Score in Dinas Bina Marga and Bina Konstruksi of North Sumatera. 2023;6(3).
16. Sadafi S, Azizi A, Pasdar Y, Shakiba E, Darbandi M. Risk Factors For Gastroesophageal Reflux Disease: A Population-Based Study. BMC Gastroenterology. 5 Februari 2024;24(1):64.
17. Sakti PT, Mustika S. Analisis Faktor Risiko Gastro-Esophageal Reflux Disease di Era Pandemi COVID-19 pada Mahasiswa Program Pendidikan Dokter Spesialis Fakultas Kedokteran Universitas Brawijaya. J Penyakit Dalam Indones. 1 Oktober 2022;9(3):164.
18. Sanada F, Taniyama Y, Muratsu J, Otsu R, Shimizu H, Rakugi H, dkk. Source of Chronic Inflammation in Aging. Front Cardiovasc Med. 22 Februari 2018;5:12.
19. Saputera MD, Budianto W. Diagnosis dan Tatalaksana Gastroesophageal Reflux Disease (GERD) di Pusat Pelayanan Kesehatan Primer. 2017;44(5).
20. Setiawan MA, Fasrini UU, Amir A, Miro S. Characteristics of Gastroesophageal Reflux Disease. 2023;24(3).
21. Syam AF, Hapsari PF, Makmun D. The Prevalence and Risk Factors of GERD among Indonesian Medical Doctors. Makara J Health Res. 1 Agustus 2016;20(2):35–40.
22. Tack J, Pandolfino JE. Pathophysiology of Gastroesophageal Reflux Disease. Gastroenterology. Januari 2018;154(2):277–88.
23. Tarigan R, Pratomo B. Analisis Faktor Risiko Gastroesofageal Refluks di RSUD Saiful Anwar Malang. J Penyakit Dalam Indones. 1 Juli 2019;6(2):78.
24. Tim Riskesdas 2018. Laporan Nasional Riskesdas 2018. Badan Penelitian dan Pengembangan Kesehatan Republik Indonesia.
25. Vaishnav B. Gastroesophageal Reflux Disease and its Association with Body Mass Index: Clinical and Endoscopic Study. J Clin Diagn Res [Internet]. 2017 [dikutip 3 September 2024]; Tersedia pada: http://jcdr.net/article_fulltext.asp?issn=0973-709x&year=2017&volume=11&issue=4&page=OC01&issn=0973-709x&id=9562
26. Yadlapati R, Gyawali CP, Pandolfino JE, Chang K, Kahrilas PJ, Katz PO, dkk. AGA Clinical Practice Update on the Personalized Approach to the Evaluation and Management of GERD: Expert Review. Clin Gastroenterol Hepatol. Mei 2022;20(5):984-994.e1.
27. Yuan LZ, Yi P, Wang GS, Tan SY, Huang GM, Qi LZ, dkk. Lifestyle Intervention for Gastroesophageal Reflux Disease: A National Multicenter Survey Of Lifestyle Factor Effects On Gastroesophageal Reflux Disease In China. Ther Adv Gastroenterol. Januari 2019;12:175628481987778.
28. Zein AFMZ, Nauphar D, Khasanah U, Pratamawati TM, Brajawikalpa RS, Ayuningtyas E, dkk. The Association Between the Pattern of Electronic Cigarette Smoking and Gastroesophageal Reflux. Indones J Gastroenterol Hepatol Dig Endosc. 12 Mei 2021;22(1):16–20.
29. Zheng Z, Shang Y, Wang N, Liu X, Xin C, Yan X, dkk. Current Advancement on the Dynamic Mechanism of Gastroesophageal Reflux Disease. Int J Biol Sci. 2021;17(15):4154–64.