CLINICOPATHOLOGICAL CHARACTERISTICS OF NEPHROTIC SYNDROME PATIENTS AT DR. MOHAMMAD HOESIN PALEMBANG HOSPITAL IN 1 JANUARY 2022 - 31 OCTOBER 2025
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Keywords:
Nephrotic syndrome, Glomerulu, KidneyAbstract
ABSTRAK
Sindrom nefrotik merupakan kelainan ginjal akibat gangguan filtrasi glomerulus, baik primer maupun sekunder, mencakup berbagai etiologi seperti membranous nephropathy, minimal change disease, focal segmental glomerulosclerosis, membranoproliferative glomerulonephritis, diabetic nephropathy, dan lupus nephritis,masing-masing dengan karakteristik klinikopatologi tersendiri. Penelitian ini bertujuan untuk memperoleh gambaran klinikopatologi 104 pasien sindrom nefrotik di RSUP Dr. Mohammad Hoesin Palembang. Desain penelitian deskriptif,
menggunakan data rekam medis periode 1 Januari 2022–31 Oktober 2025. Karakteristik dominan yang ditemukan adalah pasien dewasa, laki-laki, edema anasarka, tekanan darah <140/90 mmHg, hiperkolesterolemia, proteinuria +3, albumin >2,5 g/dL, PAS negatif, dan trichrome positif, dengan etiologi terbanyak berupa diabetic nephropathy, focal segmental glomerulosclerosis, minimal change disease, membranoproliferative glomerulonephritis, dan lupus nephritis. Karakteristik per etiologi juga ditelaah. Temuan ini merupakan rangkaian peristiwa yang saling terkait secara patofisiologi dan penting dipahami dalam merencanakan terapi pasien.
Article Details
Author Biography
Nina Atizah, Anatomical Pathology Residency Program, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia
PPDS PA Universitas Sriwijaya
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